The Greater Mekong Subregion (GMS) has a great opportunity to be a major supplier of safe and environment-friendly agriculture products (SEAP). The GMS economies are growing rapidly, and their population of over 330 million is becoming larger, richer, and more urbanized. Increasingly, GMS consumers look for food characteristics such as safety, healthiness, and environment-friendliness. GMS farmers generate huge surplus of agrifood products, and agribusiness companies are more sophisticated and better able to develop regional and global reach. Agricultural and food trade is growing rapidly. Trade integration is accelerating thanks to policy initiatives and development of transportation corridors and logistics systems. The improved infrastructure and the opportunity to move further along the value-added path are great incentives for the increasing ow of foreign direct investment (FDI).